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The Center brings together scholars from diverse fields such as anthropology, genetics, psychology, medicine, and physiology together in ways that exemplify the transdisciplinary nature of the New American University and interdisciplinarity of evolutionary medicine. The Center supports seminars, workshops, and public events to increase the visibility and impact of evolutionary medicine.
Transforming our Understanding of Health through Precision Medicine 2.0
Medicine is in the midst of an unprecedented transformation. Known broadly as Precision Medicine –disease and health are being redefined by their molecular characteristics. Such characterization enables the sub-grouping of patient populations and the development of targeted interventions. Somewhat ironically, these Personalized Medicine interventions are developed without consideration of sex differences, differences between populations, individual life history, and social circumstances.
This project aims to develop, implement, and ultimately utilize a cohesive population genetic framework for quantifying the evolutionary forces governing human pathogens. The preliminary aims, focused around TB, are two-fold: first, the biology underlying this bacterial infection requires the development of novel theoretical and statistical approaches, as the clonal nature of the organism, combined with low mutation rates and a lack of recombination, renders tools previously developed for the study of viruses, for example, largely inappropriate.
Two major challenges facing human civilization today are the maintenance and enhancement of curative and preventative treatments for infectious disease and cancer, and adequate provision of safe and nutritious food. A rising global population, increasing urbanization, and climate change challenge the sustainability of both endeavors.